The main objective of W 2 is to discover novel internal biomarkers in relation to children’s mental health. The specific focus lies in the discovery of proteomic, metabolomic and DNA-based biomarkers in bodily fluids.

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Reliable internal biomarkers related to diagnosis, risk prediction, monitoring disease course and outcome of mental health disorders in children remain an unmet clinical need. Advances in techniques allowing high-throughput biological analyses have introduced new opportunities for better understanding of these disorders, and the discovery of biomarkers.

The effect markers related to children’s mental health  generated in WP2 will in subsequent work packages be related to the external exposure environment of children in order to determine which of the observed mental-health related biomarkers are associated with the environmental exposure the individual was exposed to.